Alpha lipoic acid is a universal antioxidant because it dissolves not only in water, but also in fat. Thanks to this property, it copes well with intracellular protection. In addition, it combines well with other antioxidants, such as vitamin C, glutathione, vitamin E, enhancing their effects. Science has also proven the effectiveness of lipoic acid for memory problems.
Contents:
- Reconciliation for weight loss
- Application for sports
- Application in cosmetology
- Indications for use
- How to take it correctly
- Side effects contraindications
Lipoic acid is also popular among athletes, as heavy physical activity accelerates the formation of free radicals. Athletes, as prescribed by a doctor, are recommended to take one capsule in the morning. The average dosage ranges from 100 to 600 mg per day.
Thanks to its unique properties, the active substance has found wide application not only in medicine, but also in cosmetology, dietetics, and various sports disciplines.
Alpha lipoic acid indications for use
Like other vitamin-like substances, lipoic acid has its own consumption standards. They will be different depending on age.
- Children under 15 years of age are recommended to take 12-25 mg per day,
- Adults - about 25-50 mg.
- During periods of intense physical or emotional stress, it is worth increasing your lipoic acid intake to 75 mg.
- If lipoic acid is part of a complex treatment program for any disease, then its dosage can be significantly increased.
For weight loss
Lipoic acid tablets are often prescribed to overweight people to speed up weight loss.
If your goal is to lose excess weight! In addition to taking alpha lipoic acid, you need to eat properly and exercise. Small visual loads will significantly speed up the results. Let's look at the recommended dosages for weight loss:
- For simple physical activity without the goal of losing weight, 50 mg of the substance per day is sufficient.
- If there is active weight loss - 200 mg at a time daily.
- It is not recommended to consume more than 600 mg per day. They should be divided into 3 doses. It is better to increase the concentration gradually, starting from 50–100 mg and raising to 600.
You can also speed up the results by taking additional L-carnitine, or more serious fat burners.
To lose weight, lipoic acid should be consumed in the morning before the first meal, after training or at dinner. It is good to combine the supplement with food containing complex carbohydrates.
Alpha Lipoic Acid (ALA) as a Weight Loss Supplement
Previous studies have shown the beneficial anti-obesity properties of ALA (14–16). In animal studies, ALA supplementation has been shown to reduce body weight and fat mass by reducing food intake and increasing energy expenditure, possibly also by inhibiting hypothalamic AMP-activated protein kinase (AMPK) activity (17–20).
However, in human studies with ALA supplementation, results were inconsistent. Some clinical trials have shown that ALA supplementation can help overweight and even obese people lose weight (15, 16), while other studies have not observed any effect of ALA on weight (21, 22). To more comprehensively evaluate the effects of ALA as a weight loss supplement. A systematic review and comprehensive meta-analysis of the available literature was recently conducted (27). A total of 11 eligible studies with 12 relevant treatments were identified for inclusion in this review. Of these studies, 8 reported results for weight and seven reported results for BMI. The studies in this meta-analysis were conducted in a variety of populations, including patients with diabetes mellitus (9, 21, 23), metabolic syndrome (24), rheumatoid arthritis (25), and nonalcoholic fatty liver disease (26). Three studies were designed as weight loss interventions and were conducted with overweight and obese people. The total number of participants in these studies was 534 in the ALC group and 413 in the placebo group.
The duration of the study ranged from 8 weeks to 52 weeks. ALA doses ranged from 300 mg/day to 1800 mg/day. Total weight loss was 1.27 kg greater with ALC treatment compared to the placebo group. A significant overall mean difference in body mass index (BMI) was also found; in the ALC group, BMI decreased by 0.40 kg/m2 more than in placebo.
There was no evidence of publication bias in the analyzes of changes in weight and BMI. Cumulative results in this meta-analysis showed significant reductions in body weight and BMI with ALA treatment compared with placebo, regardless of whether it was used for weight loss or other purposes. Meta-regression analysis showed that shorter duration of ALC intervention resulted in greater reduction in BMI than longer interventions.
Rates of adverse events and all-cause discontinuation were similar between ALC and placebo. In this analysis, intervention duration, but not ALA dose, was found to be significantly associated with reduction in BMI. The studies in this meta-analysis examined different doses of ALA (from 300 mg/day to 1800 mg/day) at different intervention durations (from 8 weeks to 52 weeks). One placebo-controlled study compared the effectiveness of different doses of ALA on body weight (16). Koh et al. (16) examined the effects of 1200 mg/day and 1800 mg/day ALA intervention on weight loss. They found that the higher dose of ALA resulted in significant reductions in weight and BMI throughout the study compared to placebo, and the lower dose resulted in significant weight reduction only in the first weeks of this study, however this effect was not sustained throughout the duration of the study. research. Based on these data, it can be argued that the effect of ALA on body weight is limited to the short term, especially when it is used in lower doses.
Application in cosmetology
In cosmetology, lipoic acid is most often used externally as a cosmetic product. In most compositions of anti-aging creams, it comes first. Lipoic acid gives the skin a healthy appearance, helps maintain its tone and reduces the negative effects of long exposure to the sun. May be useful for skin diseases:
- eliminates the appearance of dandruff.
- eliminates skin rashes and acne.
- It tightens pores well and reduces inflammation.
- reduces skin aging.
Indications for use
Through clinical studies of the effectiveness of the active substance, doctors have identified a number of indications for the use of Alpha Lipoic Acid :
- Diabetes mellitus in the compensation stage - the drug helps maintain the amount of glucose in the blood within normal limits, improves the absorption of insulin by cells.
- Liver lesions . Taking the medicine helps destroy free radicals in the liver parenchyma, promotes its rapid regeneration, and normalizes bile production.
- Intoxication. The effectiveness of lipoic acid in case of poisoning is due to its ability to bind and remove toxic compounds from the body and accelerate their conversion into insoluble metabolites.
- Diseases of the cardiovascular system. Cardiologists prescribe ALA to improve lipid metabolism, lower cholesterol, and reduce atherosclerotic plaques on the walls of blood vessels.
Lipoic acid for weight loss. Main advantages of the drug
Scientists have discovered a large list of beneficial properties for the human body in the popular antioxidant.
The most important of them:
- activation of metabolism;
- improvement of the skin;
- stabilization of blood glucose levels;
- general rejuvenation of the body;
- positive effects on the cardiovascular system and pancreas;
- promoting improved vision;
- removal of waste and toxins from the body.
Note. The cost of a health course using lipoic acid is significantly lower than when using other medications. The ratio “price – effectiveness – safety – ease of use” in this case can be considered optimal.
If you follow all the points described in the instructions, the substance has a beneficial effect on the general condition of a person and does not cause harm to his body. Another important advantage is that the drug is an ideal treatment for diabetes. Many patients are forced, due to the presence of a large number of contraindications, to abandon a number of diets and medications.
How to use
- For the treatment of diabetes and its complications , atherosclerosis, exogenous intoxications, and neuropathies, thioctic acid is prescribed in a dosage of 300 mg to 600 mg per day, dividing the norm into 2-3 doses.
- For liver diseases and chronic pancreatitis, the dose is 200-400 mg. Capsules or tablets should be swallowed whole and drunk before meals. According to the instructions for use of lipoic acid from the manufacturer, it is not recommended to crush or chew the tablets. The course of treatment is 3-4 weeks. After a break of 1 month, you can repeat the course.
- Children over 6 years of age with intoxication can be prescribed from 25 to 50 milligrams of the active ingredient per day.
- As a preventative measure, doctors advise taking alpha-lipoic acid 50-100 mg per day. This dosage is quite sufficient to maintain the functioning of all metabolic processes and neutralize free radicals. Supplements are taken 1-2 times a day with meals or half an hour before meals, washed down with clean water. It is not recommended to exceed the indicated doses to prevent overdose.
For people engaged in heavy physical labor and athletes, daily norms can be increased to 300-400 mg under the supervision of a doctor. Dietary supplements are consumed for 3-5 weeks, with breaks between courses of 30 days.
Side effects
Based on the studies conducted, it can be concluded that the acid is a relatively safe compound and exhibits very low toxicity. The approximate toxic dose for humans is determined at 5-10 grams per day. Taking too high a dose over a long period of time may result in side effects such as nausea, diarrhea, abdominal pain, and allergic skin reactions.
Alpha lipoic acid has not been tested for safety in children or pregnant or breastfeeding women, so ALA products are not recommended for these people.
Side effects are rare when taking lipoic acid, but if they occur, you should stop taking the supplement and consult a specialist. The following adverse reactions are observed:
- aversion to food, complete loss of appetite;
- constant headaches;
- increased sweating and dry mouth;
- sleep problems.
KWC Alpha Lipoic Acid and L-Carnitine, Advanced Formula
Alpha lipoic acid with L-carnitine for weight loss is a complex of nutrients from the Japanese manufacturer KWC. The effectiveness of the drug is guaranteed by a special recipe and precise technological processing that preserves the quality of each component. The improved formula of the biological supplement is suitable for women and men.
The drug has a pronounced rejuvenating effect. Gradually and safely for health, it reduces body weight through the natural regulation of metabolic processes. This approach to weight correction eliminates disorders of the nervous system and psyche, and does not affect the overall well-being of a person.
Lipoic acid is available in 1.2 cm long yellow-brown gelatin capsules for oral administration. This is an improved supplement formula that includes the fat burner L-carnitine. The substances are synergists, i.e. they enhance each other's action. The bottle is made of tinted glass to protect the complex from sunlight. The product should not be exposed to direct UV rays. One bottle contains 120 capsules. The quantity is calculated for 1 course (30 days). Storage conditions: dark place, air temperature no more than 25°C.
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Contraindications
Like any medicine, lipoic acid has a number of contraindications. You should refrain from taking the drug in the following situations:
- in the presence of gastric ulcer or duodenal ulcer, chronic gastritis in the acute stage;
- in case of individual intolerance to the substance or other components of the dietary supplement;
- in case of decompensated diabetes, when there is no control over blood sugar levels;
- Also not prescribed to children under 6 years of age.
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What is lipoic acid
Lipoic acid is also known for its unique property of burning excess fat deposits. This occurs due to the substance’s effect on improving metabolic processes in the body and converting sugar obtained from food into valuable energy.
By using this drug together with a properly balanced diet and the physical exercises necessary for the body, you can lose from 5 to 7 kilograms in a month.
In nature, the substance has the form of a yellowish crystalline powder with a specific bitter taste and unpleasant odor. Natural lipoic acid dissolves well in liquids containing an alcohol base.
Lipoic acid for weight loss is produced in tablet form and capsules, in powders for the preparation of suspensions and in solutions for intravenous and intramuscular injections.
